Colorwatcher

Compact colorimetric microarray imager with brightfield and darkfield illumination

For research use only. Not for use in diagnostic procedures.

Colorwatcher takes colorimetric images of microarrays and measures the spot intensities with the QuantoPic software. The user interprets the results.

It has two illumination modes: brightfield (bottom illumination) and darkfield (top illumination). It reads 96-well plates, 12×8 well strips and microscope slides (with an adapter).

A high-sensitivity CMOS camera gives fast, high-contrast images at 6 µm per pixel. An automated mechanism ejects the plate.

Colorwatcher is compact and fits into an airline carry-on bag.

Colorwatcher is designed and manufactured under a quality management system based on ISO 13485.

  • Brightfield and darkfield illumination
  • LED light source, lifetime over 10 000 hours
  • 3 MP CMOS camera, 6 µm per pixel, field of view 7.7 × 7.7 mm
  • Diffuse reflectance 2 to 99 %DR, calibrated at production with Spectralon standards
  • 96-well plates, 12×8 well strips, up to 4 microscope slides
  • Automated plate ejection
  • Manual or automatic focus (software-controlled); programmable exposure up to about 30 s
  • End-user mode: choose an assay, load the samples, get the results
  • Password-protected Assay Developer mode with access to all parameters
  • QuantoPic is included. It controls the instrument and analyses the images.
  • AI Array Finder: automatic microarray grid detection and alignment
  • Grid layout and region mapping
  • Automated image acquisition and positioning
  • Spot intensity (total, mean, median) with background correction
  • Qualitative and quantitative assays, including 4PL and 5PL calibration curves
  • Point-and-shoot imaging at specified locations
  • Export of results to PDF, CSV and Excel
Imaging mode Colorimetric: brightfield (bottom illumination) and darkfield (top illumination)
Light source LED
Light source lifetime Over 10 000 hours
Measurement range 0 to 65 535 (arbitrary units)
Optical density (brightfield) Indicative values, up to 2.0 OD. Calibration with certified OD standards on request.
Diffuse reflectance (darkfield) 2 to 99 %DR. Calibrated at production with Spectralon diffuse reflectance standards.
Vessels 96-well plate, 12×8 well strip, 4 microscope slides (with an adapter)
Camera 3 MP, CMOS
Standard image size 1280 × 1280 pixels
Resolution 6 µm per pixel
Field of view (standard image) 7.7 × 7.7 mm
Focus Manual or automatic (software-controlled)
Exposure Up to about 30 s (programmable)
Image formats PNG or TIFF, 16-bit
Data interfaces USB 2.0 (instrument control), USB 3.0 (camera)
Software QuantoPic, included
Size (W × D × H) 330 × 345 × 150 mm
Weight (without power supply) Up to 6 kg
Power supply External power supply XP Power AKM90PS24 (CE marked): input 100–240 V AC, 50/60 Hz; output 24 V DC, 3.75 A, 90 W. Instrument input: 20–24 V DC.
CPU Intel Core i7 with AVX2 support
RAM 8 GB
Graphics card Nvidia GeForce GTX 1050 Ti 4 GB or better (Nvidia GeForce 10, 16, 20 or 30 series only)
Storage SSD, 256 GB
Operating system Windows 11, 64-bit
  • Research use only (RUO). Not a medical device and not an in vitro diagnostic medical device.
  • CE marking: EMC Directive 2014/30/EU, Machinery Directive 2006/42/EC, RoHS Directive 2011/65/EU.
  • Designed and manufactured in Riga, Latvia, by SIA Bioscience Media.